L’IMN sera présent au congrès annuel organisé par la Société Américaine des Neurosciences

L’IMN sera présent à la 47ème réunion annuelle organisée par l’American Society for Neuroscience (SFN). Cette année, elle aura lieu à Washington. Voici la liste des posters qui y seront présentés.

Posterboard Number: SS42
Exposure to novelty gates cocaine-evoked plasticity in dopamine neurons
G.R. FOIS(1), C. MILIANO(2), S. CHAUQUET(3), X. NOGUES(3), J. M. BAUFRETON(1), S. CAILLE(4), F. E. GEORGES(1)
(1)IMN-UMR-CNRS 5293, IMN, Bordeaux Cedex, France;
(2)Univ. of Cagliari, Cagliari, Italy;
(3)Univ. of Bordeaux, Bordeaux, France;
(4)CNRS UMR 5287, Bordeaux cedex, France

Posterboard Number:  131.02
Bidirectional gut-to-brain and brain-to-gut propagation of alpha-synuclein pathology in non-human primates
*S. DOVERO(1), A. PRIGENT(2), M.-L. AROTCARENA(1), M. BOURDENX(1), P. AUBERT(2), I. TRIGO DAMAS(3), G. PORRAS(1), M.-L. THIOLAT(1), M.TASSELLI(2), F. FERNANDEZ-GOMEZ(4), C. ESTRADA(5), A. RECASENS(6), J. BLESA(3), M. HERRERO(5), M. VILA(6), J. OBESO(3), P. DERKINDEREN(2), B. DEHAY(1), E. BEZARD(1)
(1)Inst. of Neurodegenerative Dis., Bordeaux, France;
(2)Inserm U913, Nantes, France;
(3)CINAC-HM Puerta Del Sur, Mostoles, Spain;
(4)Univ. de Murcia, Murcia, Spain;
(5)Univ. of Murcia, Murcia, Spain;
(6)Vall d’Hebron Res. Inst., Barcelona, Spain

Posterboard Number:  131.03
Variable selection using machine learning to identify new signatures of patient-derived aggregated a-synuclein-induced neurodegeneration in non-human primates
M. BOURDENX(1), S. DOVÉRO(1), A. NIOCHE(1), M.-L. AROTCARENA(1) , S. CAMUS(1), G. PORRAS(1), M.-L. THIOLAT(1), N. P. ROUGIER(1), A. PRIGENT(2), P. AUBERT(2), S. BOHIC(3), N. KRUSE(4), B. MOLLENHAUER(4), S. NOVELLO(5), M. MORARI(5), I. TRIGO DAMAS(6), M. GOILLANDEAU(1), M. TASSELLI(2), C. PERIER(7), N. GARCIA CARILLO(8), C. ESTRADA(9), A. RECASENS(7), J. BLESA(6), M. T. HERRERO EZQUERRO(9), P. DERKINDEREN(2), M. VILA(10), J. A. OBESO(11), B. DEHAY(1), E. BEZARD(1)
(1)Inst. Des Maladies Neurodegeneratives, Bordeaux, France;
(2)Inserm U913, Nantes, France;
(3)Inserm U836, Grenoble, France;
(4)Univ. Med. Ctr. Gottingen, Gottingen, Germany;
(5)Univ. Ferrara, Ferrara, Italy;
(6)CINAC-HM Puerta Del Sur, Mostoles, Spain;
(7)Vall D’Hebron Res. Inst., Barcelona, Spain;
(8)Ctr. Exptl. en Investigaciones Biomédica, Murcia, Spain;
(9)Biomed. Res. Inst. of Murcia, Murcia, Spain;
(10)Vall d’Hebron Res. Inst., Barcelona, Spain;
(11)CINAC, Madrid, Spain

Posterboard Number: 131.24
Effects of A53E substitution on alpha-synuclein aggregation and neurotoxicity in Parkinson’s disease models
*P. C. MONTENEGRO(1), D. YSSELSTEIN(2), N. DUTHEIL(4), S. AGIM(3), B. DEHAY(4), E. BEZARD(4), J. R. CANNON(3), J.-C. ROCHET(2)
(1)Purdue Univ., West Lafayette, IN;
(2)Medicinal Chem. and Mol. Pharmacol.,
(3)Hlth. Sci.,
(4)Inst. Des Maladies Neurodegeneratives, Bordeaux, France

Posterboard Number: 131.26
Protective effects of endosulfine-alpha (ENSA) against alpha-synuclein aggregation and neurotoxicity in Parkinson’s disease models
*A. CHANDRAN(1)(4), D. YSSELSTEIN(2)(4), P. C. MONTENEGRO(2)(4), I. COSTANTINO(5), N. DUTHEIL(6)(7), G. P. MCCABE(3), M. P. FROSCH(5), J. M.GEORGE(8), B. DEHAY(6)(7), E. BEZARD(6)(7), J.-C. ROCHET(1)(4)
(1)Medicinal Chem. and Mol. Pharmacol.,
(3) Statistics, (2)Purdue Univ., West Lafayette, IN;
(4)Purdue Inst. for Integrative Neuroscience, Purdue Univ., West Lafayette, IN;
(5)Neurol., Massachusetts Alzheimer’s Dis. Res. Center, Massachusetts Gen. Hospital,, Charlestown, MA;
(6)Univ. de Bordeaux, Inst. des Maladies Neurodégénératives, UMR 5293, Bordeaux, France;
(7)CNRS, Inst. des Maladies Neurodégénératives, UMR 5293, Bordeaux, France;
(8)Sch. of Biol. and Chem. Sci., Queen Mary Univ. of London, London, United Kingdom

Posterboard Number: 200.27
New P2X4mCherryIN knockin transgenic mice expressing non-internalized P2X4 receptors revealed alteration in hippocampal plasticity and memory
*E. BOUE-GRABOT(1), T. DELUC(1), J.-T. POUGNET(1), A. MARTINEZ(1), E. BERTIN(1), E. DOUDNIKOFF(1), E. TOULMÉ(1), A.-E. ALLAIN(2), E. BEZARD(1), S. S. BERTRAND(2), B. BONTEMPI(1), O. NICOLE(1)
(1)IMN-CNRS UMR 5293,
(2)INCIA-CNRS UMR 5287, Univ. de Bordeaux, Bordeaux Cedex, France

Posterboard Number: 210.14
Inhaling xenon ameliorates gait in the MPTP macaque model of Parkinson disease
*E. BEZARD(1), T. MIKELOVIC(2), E. M. MORAUD(2), S. SUN(2), D. W. KO(3), Q. LI(3), A. MILLET(4), G. FARJOT(4), E. PIOLI(3), G. COURTINE(2) , B. BESSIERE(4)
(1)Inst. of Neurodegenerative Dis., Bordeaux, France;
(2)Ctr. for Neuroprosthetics and Brain Mind Inst., Swiss Federal Inst. of Technol., Lausanne, Switzerland;
(3)Motac Neurosci. Ltd, Greater Manchester, United Kingdom;
(4)Air Liquide Santé Intl., Jouy en Josas, France

Posterboard Number: 210.18
K4 A novel mGluR4 PAM alleviates motor symptoms in primate models of Parkinson’s disease
*D. CHARVIN(1), T. DI PAOLO(2), E. BEZARD(3), C. HALLDIN(4), G. DUVEY(1), L. GRÉGOIRE(2), A. TAKANO(4), E. PIOLI(3), R. MEDORI(1), F. CONQUET(1)
(1)Prexton Therapeut. B.V., Naarden, Netherlands;
(2)Neurosci. Res. Unit, CHU de Québec, CHUL Pavillon and Fac. of Pharmacy, Laval Univ., Quebec, QC, Canada;
(3)Motac Neurosci. Ltd, Manchester, United Kingdom;
(4)Ctr. for Psychiatry Research, Dept. of Clin. Neurosci., Karolinska Institutet, Stockholm, Sweden

Posterboard Number: 499.02
II3 A wireless brain-spine interface that alleviates gait deficits of Parkinson’s disease
*T. MILEKOVIC(1)(2), F. RASCHELLA(3), G. SCHIAVONE(4), Y. JIANZHONG(5)(6), W. D. KO(5)(6), L. QIN(5)(6), C. QIN(5), M. CAPOGROSSO(7)(2), S. P.LACOUR(4), J. BLOCH(8), S. MICERA(3)(9), E. BEZARD(10)(5)(6), G. COURTINE(2)(8)
(1)Fac. of Medicine, Dept. of Basic Neurosci., Univ. of Geneva, Geneva, Switzerland;
(2)Ctr. for Neuroprosthetics and Brain Mind Institute, Sch. of Life Sci.,
(3)Bertarelli Fndn. Chair in Translational NeuroEngineering, Ctr. for Neuroprosthetics and Insti,
(4)Bertarelli Fndn. Chair in Neuroprosthetic Technology, Ctr. for Neuroprosthetics and Inst., Ecole Polytechnique Federale de Lausanne (EPFL), Geneva, Switzerland;
(5)Inst. of Lab. Animal Sci., China Acad. of Med. Sci., Beijing, China; (6)Motac Neurosci. Ltd., Manchester, United Kingdom;
(7)Dept. of Med., Univ. of Fribourg, Fribourg, Switzerland;
(8)Dept. of Clin. Neurosci., Lausanne Univ. Hosp. (CHUV), Lausanne, Switzerland;
(9)Neural Engin. Area, The BioRobotics Inst., Scuola Superiore Sant’Anna, Pisa, Italy;
(10)Inst. des Maladies Neurodégénératives, UMR 5293, Univ. Of Bordeaux, Bordeaux, France

Posterboard Number: 690.21
Correlation between song acoustics and neural activity in the song-related basal-ganglia-thalamo-cortical circuit in songbirds
E. WOOD(1), R. DARSHAN(2), D. HANSEL(1) , A. LEBLOIS(1)
(1)CNRS / Univ. Paris Descartes, Paris, France
(2)ELSC, the Hebrew Univ., Jerusalem, Israel

Posterboard Number: 757.18
O6 Brain insulin resistance and Parkinson’s disease
F. BASSIL, P. GUERIN, M.-H. CANRON, N. DUTHEIL, A. VITAL, E. BEZARD, P.-O. FERNAGUT, *W. MEISSNER
Inst. Des Maladies Neurodégénératives, Bordeaux, France